> For the complete documentation index, see [llms.txt](https://chembl.gitbook.io/unichem/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://chembl.gitbook.io/unichem/web-application/similarity-search.md).

# Similarity Search

UniChem [Similarity Search](https://www.ebi.ac.uk/unichem/search/similarity) is an InChI-based search function that will let you find entries for structures similar to your query structure.&#x20;

* It is a similarity search using 256 bit Morgan fingerprints and radius=2.&#x20;
* Fingerprints are created from the Standard InChI using Tanimoto as a metric.
* The search requires either an InChI string or a molecule structure, and a % threshold at which to cut off results.&#x20;

It will return all chemical structures below that threshold from UniChem. Clicking on a structure will show hits for that compound within UniChem sources.

<figure><img src="https://1911127213-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-LswQ6nYY3FF-U9wayJ5%2Fuploads%2FZAj4lVSWlV7vf3LBSiLd%2FScreenshot%202025-01-16%20at%2012.35.32.png?alt=media&amp;token=e337106e-ddf4-46cf-9f4b-f1733df20f89" alt=""><figcaption><p>Compound results</p></figcaption></figure>

<figure><img src="https://1911127213-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-LswQ6nYY3FF-U9wayJ5%2Fuploads%2F8VNdI6wPe42YtuTeDgGk%2FScreenshot%202025-01-16%20at%2012.38.22.png?alt=media&amp;token=474efd11-ab32-4bde-9e77-f345ca5da9f0" alt=""><figcaption><p>UniCHem records for a given compound</p></figcaption></figure>
