ACTIVITY.tsv

The ACTIVITY file outlines the numerical or text value of the data arising from a compound (CIDX) used in an assay (AIDX).

For more complex data types, discussed in Complex results sets, supplementary ACTIVITY_PROPERTIES, ACTIVITY_SUPPLEMENTARY and ACTIVITY_SUPP_MAP files can be used to append additional data to the activities using the activity ID (ACT_ID) and test occasion ID (TEOID) set in this file to link them.

  • CIDX, AIDX, ACT_ID , CRIDX , TYPE and ACTIVITY are mandatory.

  • A VALUE is numeric and requires an entry in the RELATION field.

  • TEXT_VALUEs should not have a RELATION sign.

  • ACTION_TYPE must be one from the defined list.

  • ACT_ID is mandatory if providing an ACTIVITY_PROPERTIES or ACTIVITY_SUPPLEMENTARY record that maps to a given row.

  • It is not possible to load data without a CTAB file, and the CTAB must match the CIDX IDs here.

  • The RICX is referred to as CRIDX in this table, it should be identical to the RIDX in all the other files of the deposition.

Header

Description

Existence

Data type

CIDX

The CIDX established by the depositor in the COMPOUNDS file - a foreign key

Mandatory

Any character up to a length of 200

CRIDX

The RIDX to be associated with the CIDX in the creation of the compound record. Must belong to SRC_ID_CIDX.

Mandatory

Any character up to a length of 200

AIDX

The AIDX established by the depositor in the ASSAY file - a foreign key

Mandatory

Any character up to a length of 200

TEXT_VALUE

The text value of non-numerical values. Do not use for value ranges. Provide these as upper and lower bounds, as VALUE fields.

Optional

Any character up to a length of 1000

RELATION

Symbol indicating relationship between the Type and the Value (permitted: '>','<','=','~','<=','>=','<<','>>')

Optional (Mandatory if a VALUE is given)

Any Relation symbol

(=, >, <, ~, <=, >=, >>, <<) up to a length of 50

VALUE

The numerical value of the activity measurement (see ACTIVITY_COMMENT for non-numerical values)

Optional

Any number (including decimals, negatives and scientific notation (e.g. 3×10^2))

UPPER_VALUE

Where the activity is a range, this represents the highest value of the range (numerically), while the VALUE column represents the lower value

Optional

Any number (including decimals, negatives and scientific notation (e.g. 3×10^2))

UNITS

The units of the measurement

Optional

Any character up to a length of 100

SD_MINUS

Standard Deviation Lower limit

Optional

Any number (including decimals, negatives and scientific notation (e.g. 3x10^2))

SD_PLUS

Standard Deviation Upper limit

Optional

Any number (including decimals, negatives and scientific notation (e.g. 3x10^2))

ACTIVITY_COMMENT

A comment on the activity measurement. Non-numerical 'values' should be given here. Equivalent to 'TEXT_VALUE' field in many other tables.

Optional

Any character up to a length of 4000

ACT_ID

A local ID used to relate records in ACTIVITY_PROPERTIES and Supplementary tables. A primary key in this table. Not required unless depositing such data.

Optional (Mandatory if there are ACTIVITY_PROPERTIES or ACTIVITY SUPPLEMENTARY files)

VARCHAR(50) Must be unique for each activity line, even if they have identical Properties.

TEOID

TEst Occasion ID, grouping together related Activity records. Usually used to group activities by time point and treatment. A primary key in this table.

Optional

Any integer up to a length of 11

TYPE

The type of measurement. Must be unique within an AIDX. E.g. if you have a test compound and another compound in the well, use CONCENTRATION and CONCENTRATION_[OTHER COMPOUND NAME]

Mandatory

Any character up to a length of 250

ACTION_TYPE

Specifies the effect of the drug on its target for protein-based assays. Must match one of the names in the ACTION_TYPE table

Optional

Any character up to a length of 50 - must be in the ACTION_TYPE table (see below)

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