# MAIP

[The malaria inhibitor prediction (MAIP) platform](https://www.ebi.ac.uk/chembl/maip/) is the result of a public-private collaboration whose aim is to develop a consensus model for predicting blood stage malaria inhibition. Five Pharma and not-for-profit partners trained a model (using code developed by EMBL-EBI) on their private datasets. The resulting models were combined by EMBL-EBI and made available through this public prediction platform.

The work to create MAIP is described in full in an [article](https://jcheminf.biomedcentral.com/articles/10.1186/s13321-021-00487-2). Note: the fingerprints described in the manuscript and in MAIP slightly differ; the ones in the publication keep the feature frequencies while the  ones currently implemented don't.

A summary of the key elements of the work is described in the section [Using MAIP results](https://chembl.gitbook.io/malaria-project/using-maip-results).

To use the platform, the user submits a compound [input file](https://chembl.gitbook.io/malaria-project/input-data-file). The system automatically reads the file, [standardises the molecules](https://chembl.gitbook.io/malaria-project/molecule-standardisation) and submits the compounds to the model. When the job is done, the user can download the [result file](https://chembl.gitbook.io/malaria-project/output-file)  via the link provided.
