TARGET_TYPE list

Specifies the type of target the experiment is assessing in the ASSAYS file.

3D CELL CULTURE

Target is a 3D cell culture model such as an organoid, sphereoid or tumoroid that mimics tissues or organs.

ADMET

For an ADMET assay (e.g., physiochemical property) there does not need to be a named target.

CELL-LINE

Target is a specific cell-line.

CHIMERIC PROTEIN

Target is a fusion of two different proteins, either a synthetic construct or naturally occurring fusion protein.

LIPID

Target is a lipid.

MACROMOLECULE

Target is a biological macromolecule (e.g., glycoproteins, hemozoin, hydroxyapatite).

METAL

Target is a metal e.g., iron.

MOLECULAR

Target has been identified as a defined molecular entity (e.g., protein or nucleic acid).

NO TARGET

Target is not applicable for a screening assay (e.g., negative control/counterscreen).

NON-MOLECULAR

Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc).

NUCLEIC-ACID

Target is DNA, RNA or PNA.

OLIGOSACCHARIDE

Target is an oligosaccharide (e.g., heparin, starch).

ORGANISM

Target is a complete organism.

PHENOTYPE

Target is a biological phenotype or process.

PROTEIN

Target is a protein or group of proteins.

PROTEIN COMPLEX

Target is a defined protein complex, consisting of multiple subunits.

PROTEIN COMPLEX GROUP

Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor).

PROTEIN FAMILY

Target is a group of closely related proteins.

PROTEIN NUCLEIC-ACID COMPLEX

Target is a complex consisting of both protein and nucleic-acid components (e.g., ribosome).

PROTEIN-PROTEIN INTERACTION

Target is the disruption of a protein-protein interaction.

SELECTIVITY GROUP

Target is a pair of proteins for which the selectivity has been assessed.

SINGLE PROTEIN

Target is a single protein chain.

SMALL MOLECULE

Target is a small molecule such as an amino acid, sugar or metabolite).

SUBCELLULAR

Target is a subcellular fraction.

TISSUE

Target is a healthy or diseased tissue.

UNCHECKED

Target has not yet been assigned.

UNDEFINED

No target has been defined.

UNKNOWN

Molecular identity of target is unknown (e.g., pharmacologically defined target).

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